How biotin works in the body
First of all, let’s remember that the body receives vitamins thanks to food and intestinal flora. Many foods contain biotin: meat, offal (liver), eggs, vegetables, etc. After eating food, it is absorbed by the digestive system vitamin B8. The body can then use the vitamin compound for various reactions.
Vitamin B8 is small and easily binds to carbohydrates, proteins, nucleic acids or other molecules. This the phenomenon is called biotinylation and is the starting point for all vitamin actions. By fixing in this way, biotin allows certain compounds to be activated or to cause a reaction. That is why the intake of vitamin B8 is necessary for the functioning of the body and maintain good health.
Synthesis of carboxylases
By biotinylation, vitamin B8 acts as a cofactor Synthesis of 5 carboxylases. These are enzymes that fix carbon dioxide on other components during cell reactions. Therefore they are necessary for human metabolism. Among other things, they play a role in the Krebs cycle (cellular energy production) and carbohydrate metabolism.
Vitamin B8 and fatty acid metabolism
Two biotin-dependent carboxylases are involved in the activity of fatty acids.
- Acetyl coenzyme A carboxylase 1 (ACC1) allows fatty acid synthesis inside the cells. It is found in adipose tissue and organs (liver, heart, pancreas, etc.).
- Acetyl coenzyme A carboxylase 2 (ACC2) is an intermediate fatty acid oxidation process. Its action is mainly focused on the muscles.
Therefore, biotin intervenes throughout the body and affects the metabolism of fatty acids. This is the part lipid family contributes to energy storage and good cell structure.
The role of biotin in carbohydrates
The human body needs energy in the form of glucose to function. When blood sugar levels drop, the body uses its glucose stores. It can also be synthesized from non-carbohydrate products: it is gluconeogenesis. This is where biotin comes in. Indeed, it binds to the enzyme pyruvate carboxylase and allows it to catalyze the reaction in the Krebs cycle. At the end of this cell cycle, glucose is replenished and is available to meet the body’s energy needs.
Biotin, amino acids and proteins
Essential amino acids can only be obtained from food. They allow protein synthesis and muscle growth. That is why it is popular among sports enthusiasts to use food supplements that contain amino acids. Back to our vitamins. Vitamin B8 plays an important role in protein metabolism. Indeed, biotin allows the catabolism of certain proteinogenic amino acids: leucine, methionine, threonine, valine and isoleucine.
Contribution of vitamin B8 to DNA
Biotin provides other benefits at the cellular level. Indeed, vitamin B8 is one of the elements responsible for regulating DNA structure and gene expression. In other words, biochemical reactions involving vitamin B8 stabilize DNA molecules during its replication. It ensures for proper DNA functioning and limits cellular disruption as well as potential effects on the body and health.
Vitamin B8: What is the effect on hair and nails?
A varied and balanced diet provides a sufficient amount of vitamin B8. Thus, the multifaceted action of biotin in the body allows maintain good general health. However, biotin is often recommended for skin problems, hair loss or nail beauty. Why? Simply because these supplements are the most composed of keratin. Vitamin B8 participates in the metabolism of this rapidly renewable protein, and therefore dandruff care. In the case of a deficiency, the first effect on the condition of the skin and the beauty of the hair and nails is noticeable.
you know now what is vitamin b8 used for. In addition to its benefits for skin, hair and nails, biotin remains an important vitamin for the health of children and adults. Fortunately, vitamin B8 deficiency is rare and can be corrected by changing your diet or taking food supplements under the advice of your doctor.