COVID-19: Vitamin C supplementation reduces mortality

After an exceptionally mild autumn, when the COVID epidemic seemed to recede into the background of our concerns, the meteorological winter is approaching, and with it the numbers of infection with COVID-19 are starting to rise again. Website CovidTracker today reports 45% more pollution than last week.

What vitamins, supplements can you take to reduce the risk of infections and complications? Vitamin C, or ascorbic acid, is a molecule with complex effects on immunity. Polish researchers wanted to know if it is beneficial for patients hospitalized with a COVID infection. They wondered about the potential of this vitamin because “Strengthening the immune system with high doses of vitamin C can, paradoxically, reduce immunity. Nevertheless, in therapeutic doses, vitamin C increases immunity. »

Vitamin C also has a beneficial antiviral effect “suppresses the growth of viruses and stimulates the production of interferon. In addition, vitamin C enhances the antiviral activity of lung epithelial cells. »

Read: Should you take vitamin D supplements for COVID-19?

Vitamin C for COVID patients in the hospital

Polish scientists conducted a A meta-analysis of 19 clinical trials. According to their results, vitamin C supplementation may reduce mortality from COVID-19 in patients 18 years and older. In-hospital mortality with supplementation was 24.1% compared with 33.9% without supplementation. In the only randomized clinical trials, hospital mortality with augmentation was 23.9% versus 35.8% without augmentation.

Mortality was 13.0% with intravenous vitamin C compared with 18.9% without vitamin C. A pooled analysis of oral vitamin C showed a significant reduction in in-hospital mortality of 39.3% compared with 51.8% without vitamin C.

However, patients treated with vitamin C had a longer length of stay in the intensive care unit compared to standard treatment. Further studies, especially randomized clinical trials, are needed to confirm these results.

Benefits of Vitamin C for Winter Respiratory Infections

Vitamin C is a powerful antioxidant. In 1970, the American researcher and double Nobel laureate Linus Pauling published a book showing that vitamin C helps prevent colds.

Read: Linus Pauling, Nobel Laureate and Pope of Vitamin C

To Let’s stop sabotaging our immunityexplains Thierry Souccar “The main cause of death after infection with the new coronavirus SARS-CoV-2, as well as with the flu virus, is a massive inflammatory response called a ‘cytokine storm.’ which occurs in the lungs and can cause a very serious clinical syndrome with multiple organ failure and subsequent death. »

However, vitamin C has anti-inflammatory effects that may be of interest against COVID-19: “In the case of a cytokine storm or sepsis, neutrophils (white blood cells) accumulate in the lungs and destroy the alveolar capillaries. Vitamin C can effectively prevent this process and limit lung damage. In addition, vitamin C can help remove alveolar fluid and preserve lung barrier function. » finally, “cytokine storms are accompanied by high levels of oxidative stress”therefore, an antioxidant such as vitamin C is of interest.

There is vitamin C fruits and vegetables such as kiwi, pepper, black currant, lemon, orange, grapefruit… Our requirements are 110 mg per day for adults.

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