A good level of vitamin D can prevent dementia

⇧ [VIDÉO] You may also like this partner content (post-post)

Dementia, which affects memory, thinking, behavior and the ability to perform daily tasks, is a leading cause of disability and dependency in older adults. It is the result of pathologies or injuries affecting the brain, such as Alzheimer’s disease (60-70 percent of cases) or stroke. Many scientists have long argued that a good intake of vitamin D would benefit brain health. But for the first time, a study shows a direct link between dementia and stroke risk and vitamin D deficiency. Genetic analyzes and neuroimaging, described American Journal of Clinical Nutrition.showed that up to 17% of dementia cases can be prevented in certain populations with adequate vitamin D intake.

Dementia is a progressive or chronic pathology in which impairment of cognitive functions is observed. This is especially important for memory, reasoning, orientation, understanding, etc. It is also often accompanied by a deterioration in emotional control, social behavior or motivation. The manifestations of this disease are often an obstacle to diagnosis, so it is especially difficult for patients who are sometimes misunderstood and stigmatized.

The disease may manifest differently in each patient, depending on personality or background. The symptoms can then be divided into three evolutionary stages, the first of which is often overlooked, prone to forgetfulness, disorientation and disorientation. In the second stage, the symptoms become more visible: patients get lost at home, they have difficulty communicating, they need help with hygiene care… When they reach the last stage, as the symptoms worsen, patients become almost completely inactive and dependent.

In addition, dementia can take many forms depending on its causes. The most common form is associated with Alzheimer’s disease. Others are vascular, with Lewy bodies (abnormal accumulation of protein in nerve cells) and frontotemporal (degeneration of the frontal lobes of the brain). Also, it can happen that the same person has a mixed form of dementia.

Dementia in the world affecting nearly 50 million people. 60% of them live in low- and middle-income countries, suggesting that the disease is not necessarily just related to aging. 10 million new cases are registered every year. It is expected that by 2030 and 2050 the number of cases will reach 82 million respectively. and 152 million

Recently, researchers at the University of South Australia have demonstrated for the first time a direct link between dementia and vitamin D deficiency. Vitamin D is a precursor hormone whose widespread effects, including brain health, are increasingly recognized, but until now it has been very difficult to study what would happen if vitamin D deficiency could be avoided. “, explains a communicated Elina Hyppönen, lead researcher and director of the Australian Center for Precision Health at the University of South Australia.

According to the expert, the results of the study reveal an effective means of preventing dementia, as well as the need to eliminate vitamin D deficiency in the world.

Genetic analysis of 294,514 people

The new study’s genetic analysis included data from nearly 294,514 people aged between 37 and 73 from the UK Biobank. The aim was to reveal the relationship between vitamin D levels and neuroimaging features associated with dementia and stroke. Age, gender, ethnicity, socioeconomic factors, lifestyle, behavior (including sun exposure) and other disease-related factors were also taken into account when analyzing the results.

The researchers then found that low levels of vitamin D were associated with smaller brain volumes and an increased risk of dementia and stroke. This association was even stronger in people with levels of the vitamin below or equal to 25 nanomoles per liter (the normal level is 50 nanomoles per liter).

Genetic analyzes have also confirmed the link between vitamin deficiency and dementia. Given that vitamin D deficiency is common in a given population, up to 17% of dementia cases could be prevented by normalizing vitamin D levels.

Dementia is a progressive and debilitating disease that can devastate individuals and families “, says Hyppönen. ” If we could change this reality by ensuring that none of us were seriously deficient in vitamin D, it would be beneficial and could make a difference to the health and well-being of thousands of people. “, she says. According to the researchers, people who are deficient in vitamin D could not simply adjust their diet. Therefore, other contributions would be needed.

Source: American Journal of Clinical Nutrition.

Leave a Comment