How nicotinic acid works in your body
To understand the side effects vitamin B3, you need to understand how it works in your body. The one we named vitamin PP It is not strictly a vitamin. In fact, your body can make it from tryptophan.
It is in the form of food nicotinic acid or nicotinamide. It is absorbed by the intestines and processed by the liver. Although it is a water-soluble vitamin, you only have it for about 2-6 weeks. The excess is washed out through the kidneys.
Side effects of niacin on your body
In your body, niacinamide affects red blood cells, hormones, neurotransmitters, lipids, or even carbohydrates. Also, excess Side effects are highly variable. Focus.
Skin problems due to excess vitamin B3
In your organization excess vitamin B3 can cause skin problems. At the threshold of toxicity, redness, itching and stinging often occur. By the way, high doses of nicotinic acid induce hot flashes. It aggravates your facial skin conditions.
Taking too much nicotinic acid increases the risk of diabetes
According to some studies, long-term use excessive doses of vitamin B3 promote the development of diabetes. Indeed, niacin causes hyperglycemia problems. Your body becomes insulin resistant. After all, you have to risk of developing diabetes.
Gastrointestinal symptoms with high doses of vitamin PP
Like most vitamins, excess vitamin B3 causes gastrointestinal disorders. Remember that nicotinic acid or nicotinamide from your diet is absorbed by your gut. Excess then causes work overload.
Taking too much nicotinamide carries a risk of liver toxicity
The liver is transforming in your body nicotinic acid and nicotinamide to nicotinamide-adenine-dinucleotide, the active form of vitamin B3. If you have too much vitamin PP, your liver is overloaded. If the congestion is prolonged, your liver gets worse. Damage occurs when the toxicity threshold is exceeded.
Dietary supplements and vitamin B3 excess
Vitamin B3 is found in most foods. Moreover, deficiency is rare in developed countries. However, it still causes pellagra in some African countries. But even if pellagra is a serious disease, this is no reason to go crazy with niacin supplements. In fact, its side effects can be dangerous. Therefore, authorities have set a safety limit of 10 mg/day for nicotinic acid and 900 mg for nicotinamide.
Niacin and drug interactions
L’use of vitamin supplements is generally safe for your health. However, niacin interacts with certain medications, ask your doctor for advice:
- lack of vitamin B2 or B6 limits the absorption of vitamin B3;
- a tryptophan deficiency can cause niacin deficiency;
- alcohol increases the risk of vasodilation-related side effects;
- niacin is not recommended for people with liver disease or diabetes.
In nutritional doses, vitamin B3 is safe for health. However, high doses over a long period of time are likely cause side effects. Skin, intestinal or even liver problems appear as soon as the toxicity threshold is reached. Talk to your doctor before taking supplements.