This common vitamin would be preferred against anxiety and depression

Vitamins are involved in many biological functions, including building the body (growth, skeletal development, etc.) and functioning and maintaining the body (transformation and utilization of macronutrients, vision, blood clotting, muscular systems, nervous, immune, DNA production, etc.). This large family includes the B vitamins, which are involved in the use of proteins, lipids and carbohydrates, energy production at the cellular level, red blood cell production and nerve cell function. There are eight of them: vitamins B1, B2, B3, B5, B6, B8, B9 and B12. In a new study, researchers at the University of Reading investigated the potential positive effects of vitamin B6 on mental health, specifically anxiety and depression. A study published by them in the overview Human Psychopharmacology: Clinical and Experimentalsays that such a supplement, under the supervision of a doctor, can alter the level of brain activity associated with chemical messengers to prevent or treat mood disorders.

Brain function depends on a delicate balance between excitatory neurons, which carry information, and inhibitory neurons, which prevent escape. activity. explains lead study author Dr. David Field. ” Theories link mood disorders and certain other neuropsychiatric conditions to a disruption of this balance, often due to increased levels of brain activity. Vitamin B6 helps the body produce a specific chemical messenger that inhibits impulses in the brain, and our study links this calming effect to reduced anxiety in participants. Specifically, vitamin B6 is involved in amino acid metabolism and neurotransmitter synthesis. ANSES* states that qa” Vitamin B6 deficiency causes hypochromic microcytic anemia, convulsions associated with lack of gamma-isobutyric acid synthesis and skin symptoms (eczema, dermatitis). ยป Vitamin B6 is sold in tablet form, alone or in combination with other vitamins or mineral salts such as magnesium.

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The researchers wanted to see if supplementing with vitamin B6, which is known to be involved in the body’s production of GABA, one of the most common inhibitory neurotransmitters in the brain, which plays a critical role in regulating many aspects of the body, including mood, could reduce this. the level of stress and depression symptoms in a group of 300 participants. To do this, the latter were randomly given vitamin B6 or B12 supplements well above the recommended daily allowance (about 50 times the recommended daily allowance) or a placebo every day for one month. The results showed that vitamin B12 had a small effect compared to placebo during the trial period, but vitamin B6 made a statistically reliable difference. The increased GABA levels in the participants who took vitamin B6 supplements were confirmed by visual tests performed at the end of the study, supporting the hypothesis that B6 was responsible for reducing anxiety.

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It turns out that ” subtle but harmless changes in visual activity were detected, corresponding to a controlled level of brain activity. “, notes the team of scientists. The good news is that many foods contain vitamin B6. According to ANSES, the main food sources of vitamin B6 are of plant origin (all forms of grains, starchy vegetables, products derived from soy, fruits) and of animal origin (beef, veal, pork and poultry liver, fish). on his side, the medical journal Vidal indicates thatVitamin B6 is found in meat, poultry, fish, eggs, potatoes and fruits, except citrus fruits. The recommended average dietary requirement (NRA) for vitamin B6 is 1.5 mg per day for men and pregnant women and 1.3 mg per day for women. However, when it comes to the use of supplements, Professor David Field makes it clear that their research is only at an early stage and that further research is needed to confirm these results. In fact, the research team does not currently recommend the use of dietary supplements.

However, she believes that nutrition-based interventions would have far fewer side effects than medication, making them an interesting adjunctive treatment for people suffering from anxiety or depression in the future. “ For this to be a viable option, further research is needed to identify other nutrition-based interventions that benefit mental well-being. One possible option would be to combine vitamin B6 supplements with talk therapy, such as cognitive behavioral therapy, to enhance their effects. concludes Professor David Field. Please note that Vidal magazine, in turn, warns against over-supplementation of vitamin B6, often associated with self-medication. She believes that in high doses, more than 500 mg per day, vitamin B6 can cause loss of sensation in the fingers and toes, nausea and vomiting, and loss of appetite. According to her, only teenagers, pregnant women and the elderly are particularly affected by insufficient food.

*National Food, Environmental and Occupational Health Safety Agency

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