Alzheimer’s disease: Vitamin D deficiency increases …

A new Australian study confirms what Inserm researchers have already observed: vitamin D deficiency greatly increases the risk of developing dementia and especially Alzheimer’s disease.

Australian researchers Researchers analyzed genetic data from almost 295,000 participants from the UK biobank’s biomedical database to measure the effects of low levels of vitamin D on neurological imaging of the human brain and the risk of dementia and stroke. The results of this extensive study, published in American Journal of Clinical Nutrition, specify it vitamin D has clear of consequences for the development of neurocognitive diseases as dementia. And that high levels of vitamin D reduce the risk of Alzheimer’s disease and stroke.

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“In my opinion, strategies for fortifying foods with vitamin D need to be seriously considered, and in countries where this has already been done, it has been possible to increase concentrations at the population level. emphasizes Professor Elina Hypponen, the lead author of this study.

While waiting for vitamin D to be added to certain foods, here’s it The 15 Best Foods High In Vitamin Dwhich you can add to your menu.

Risks already identified by Inserm

The study of three cities (3C) is a cohort in which 2000 nearly 10,000 people aged 65 and over were in good health or at least ill. Alzheimer’s disease. Participants in this study were regularly reviewed by psychologists and underwent numerous neuropsychological tests to diagnose and diagnose all new cases of dementia, and more specifically Alzheimer’s disease.

2017 two researchers from Inserm Bordeaux were able to analyze the blood status of the participants in this study, with a particular focus on nutrient concentrations: Fatty acidscarotenoids, vitamins E, D, and A. Indeed, several of these nutrients may predict a risk of dementia, but their overall role has not yet been addressed.

Initially, researchers were interested in vitamin D. Studies have already shown a deficiency in this vitamin increases the risk of cancerabouthigh blood pressure or uterine fibroids, but the risk of developing neurological disease has not been clearly established.

This first study of Inserm showed that participants who were deficient in vitamin D (25%) or deficient in vitamin D (60%) had a 2-fold increased risk of developing dementia and an increased risk of Alzheimer’s disease of almost 3 compared with those with The amount of D is satisfactory. Then, in a second study, researchers at Inserm from the 1219 Bordeaux Population Health Unit (BPH) revealed a special profile: the elderly, who had the lowest levels of vitamin D, carotenoids and polyunsaturated fatty acids (‘good fats’) in their blood. There is a 4-fold higher risk of developing dementia and Alzheimer’s disease compared to those with the highest levels of these nutrients in their blood.

According to researchers, “The excess risk posed by this multiple deficiency of fat-soluble nutrients appears to be much higher than the risk associated with genetics.”. Thus, maintaining adequate blood levels of vitamin D in the elderly can help delay or prevent dementia, especially of the Alzheimer’s type. Both works were published in a journal Alzheimer’s disease and dementia.

Source : Vitamin D and Brain Health: A Surveillance and Mendel Randomization StudyAmerican Journal of Clinical Nutrition, 2022. June

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