No, the pill sun is not a real shield from Covid. However, hope for easy and inexpensive COVID-19 vitamin D prophylaxis seemed plausible. Several studies have shown that people who develop severe COVID often lack this protein, which is known to play innate immunity to respiratory viruses. Even better, vitamin D has been shown to stimulate the expression of peptides that bind to the coronavirus Spike protein and prevent it from binding to our cells ’ACE-2 receptors. British researchers developed a Phase 3 clinical trial to test this hypothesis (called CORONAVIT), the findings of which were published online in 2022. March 23 pre – printing (not yet reviewed). Unfortunately, their results show that vitamin D supplements do not affect the chances of developing Covid.
Supplements increase the amount of vitamin D.
In this randomized study, the researchers wanted to determine whether correcting for vitamin D deficiency with dietary supplements could protect against Sars-CoV-2 coronavirus. A total of 6,200 participants aged 16 years and older (median age 60.2 years) were divided into three groups: a control group, a group treated with a low dose of vitamin D (800 IU daily), and one who had a higher dose of vitamin D. doses of this vitamin (3 200 IU per day; IU or IU in French as the ‘international unit’ used to measure the amount of pharmacological product). Participants received food supplements at home for six months – from 2020. December. until 2021 June
No, the pill sun is not a real shield from Covid. However, hope for easy and inexpensive COVID-19 vitamin D prophylaxis seemed plausible. Several studies have shown that people who develop severe COVID often lack this protein, which is known to play innate immunity to respiratory viruses. Even better, vitamin D has been shown to stimulate the expression of peptides that bind to the coronavirus Spike protein and prevent it from binding to our cells ’ACE-2 receptors. British researchers developed a Phase 3 clinical trial to test this hypothesis (called CORONAVIT), the findings of which were published online in 2022. March 23 pre – printing (not yet reviewed). Unfortunately, their results show that vitamin D supplements do not affect the chances of developing Covid.
Supplements increase the amount of vitamin D.
In this randomized study, the researchers wanted to determine whether correcting for vitamin D deficiency with dietary supplements could protect against Sars-CoV-2 coronavirus. A total of 6,200 participants aged 16 years and older (median age 60.2 years) were divided into three groups: a control group, a group treated with a low dose of vitamin D (800 IU daily), and one who had a higher dose of vitamin D. doses of this vitamin (3 200 IU per day; IU or IU in French as the ‘international unit’ used to measure the amount of pharmacological product). Participants received food supplements at home for six months – from 2020. December. until 2021 June
At the start of the study, the researchers looked at vitamin D levels in about half of the participants, almost all of whom (97.4%) were taking insufficient amounts (25-hydroxyvitamin-D3 or 25-OH-D blood levels below 75 nmol / liter). Nearly 3,000 participants received one of the treatments they had to undergo at least six times a week (which 90% of these participants would have followed). Due to these supplements, participants treated at the end of the study had much higher vitamin D levels than those who did not receive treatment: approximately 102.9 nmol / l for those receiving the higher dose and 79.4 nmol / l for those receiving the low dose. vitamin D, and 66.6 for untreated patients.
However, they do not protect against coronavirus
Despite this increase in vitamin D levels, the chances of developing coronavirus or severe Covid did not differ. In all groups, about 5% of participants became infected (5% on the high dose, 5.7% on the lower dose, and 4.6% on the untreated). Among these infected participants, the number of patients hospitalized for Covid-19 and intensive care was similar in the three groups. Conclusion: Vitamin D supplements are not helpful in preventing COVID.
Because the study was conducted in the semester in which the most vulnerable people were vaccinated in the UK (January-June 2021), the vaccination rate was very different from the start (2.5% of participants) and the end of the study. up to 89.1%). Therefore, it was possible that in one of the groups, this vaccination rate increased more rapidly and those who did not receive vitamin D treatment were protected. The researchers investigated this possibility with a more accurate analysis, which showed that vaccines had nothing to do with it: vaccinated or unvaccinated, vitamin D supplements had no effect.
Some participants in the control group revealed that they were taking vitamin D supplements during the study. To check that they did not negate the results, the researchers performed a third analysis, this time controlling only those who did not take these supplements at all. Again, there was no significant difference between the groups. The vitamin D is useful for many reasons, but not to protect us from Ccovid.